Laboratory of Respiratory Pathophysiology

The Laboratory provides diagnostic testing for the Center, as well as for community health services, other departments within the Hospital Trust and research activities.

Pulmonary function assessment

This includes:

spirometry
body plethysmography
airway resistance
specific/non-specific bronchoprovocation tests
drug challenge testing
bicycle ergometer stress test
diffusing capacity testing
assessment of hypoxia
lung clearance index (LCI)
negative expiratory pressure (NEP) test
gas exchange testing

These tests enable assessment of lung function, from asymptomatic initial status (with normal spirometry) to respiratory failure and the post-transplant phase. Pulmonary function assessment is the main marker for the various stages of lung disease in cystic fibrosis; it is also the most important treatment response criterion (whether for established treatment protocols or for new drugs).

Diagnosis of cystic fibrosis

Sweat test.